#qcm-d

QCM-I 3000 biosensor system

QCM 3000 – Biosensor System for Combined “Wet” and “Dry” Mass Measurements

MicroVacuum’s QCM 3000 Wet & Dry Mass measuring system includes two biosensor systems in one: An acoustic biosensor (Quartz Crystal Microbalance with Dissipation Monitoring) for “wet” mass measurement with an additional optical biosensor (OWLS) for “dry” mass measurement. There is also an option for synchronized electrochemical setup for the QCM 3000 system. For references, pricing […]
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3 years ago
Diagram of QCM-I Net Multi-channel QCM-D with Unlimited Channels

Introducing QCM-I Net, MicroVacuum’s new solution for multi-channel QCM-D measurements with unlimited options

We are very excited to announce the availability of our new QCM-I NetTM multi-channel QCM-D solution. MicroVacuum’s QCM devices have long been market leading instruments for Quartz Crystal Microbalance measurements with impedance (QCM-I) and dissipation monitoring (QCM-D). Modularity and affordability were always one of our differentiators compared to other companies’ offerings, without ever compromising on […]
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3 years ago
Fluidic Configurations for QCM-I / QCM-D

Fluidic Configurations for QCM-I / QCM-D

Pump Flow Control with Manual Sample Introduction It is recommended that samples are introduced to the QCM-I flow-cells using a pump to control the flow. In the simplest setup, shown in figure 1, a peristaltic pump* is used to suck buffer directly from a beaker or other container. Sample is introduced to the flow-cell by […]
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4 years ago
QCM-I in Glove Box

Quartz Crystal Microbalance in Glove Box

MicroVacuum’s high performance QCM-I device is a Quartz Crystal Microbalance System with impedance analyses and dissipation monitoring (QCM -D), the Glove-Box QCM-I takes the high performance QCM-I instrument into a format suitable for mounting in a Glove-box or controlled atmosphere chamber and also includes the option of a wider temperature range e.g. between -30 °C and 80 °C.
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5 years ago
The Principles of QCM-I (QCM-D) - Figure 1

The Principles of QCM-I

Quartz Crystal Microbalance with Impedance Analysis (QCM-I) and Dissipation Monitoring (QCM-D) The Quartz Crystal Microbalance is a well-established and sensitive technique used to measure the interactions of molecules, polymers and biological assemblies with a sensor surface, in air or liquid, label-free and in real time. It is based on the change in resonant frequency of […]
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5 years ago

Gamry Announces Exclusive Distribution of MicroVacuum’s Quartz Crystal Microbalance Instruments which Include Impedance and Dissipation Measurement

MicroVacuum of Budapest, Hungary has named Gamry Instruments as the exclusive distributor of their Quartz Crystal Microbalance with Impedance measurement ( QCM-I ) in the United States & China Budapest, Hungary, September  8, 2018 – Gamry Instruments of Warminster, PA and MicroVacuum of Budapest, Hungary are pleased to announce a strategic partnership. The agreement awards Gamry […]
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6 years ago
In situ viscoelastic properties and chain conformations of heavily hydrated carboxymethyl dextran layers

A comparative study using OWLS and QCM-I chips coated with waveguide material

We are very proud that both of our OWLS and QCM-I biosensor systems were used in the recent comparative study published on Nature.com See the abstract below and visit Nature.com to read the full publication. In situ viscoelastic properties and chain conformations of heavily hydrated carboxymethyl dextran layers: a comparative study using OWLS and QCM-I […]
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6 years ago

Variations in Coupled Water, Viscoelastic Properties, and Film Thickness of a Mefp-1 Protein Film during Adsorption and Cross-Linking:  A Quartz Crystal Microbalance with Dissipation Monitoring, Ellipsometry, and Surface Plasmon Resonance Study

Abstract We have measured the time-resolved adsorption kinetics of the mussel adhesive protein (Mefp-1) on a nonpolar, methyl-terminated (thiolated) gold surface, using three independent techniques:  quartz crystal microbalance with dissipation monitoring (QCM-D), surface plasmon resonance, and ellipsometry. The QCM-D and ellipsometry data shows that, after adsorption to saturation of Mefp-1, cross-linking of the protein layer […]
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6 years ago

Fibronectin terminated multilayer films: protein adsorption and cell attachment studies

Abstract Electrostatically driven layer-by-layer (LbL) assembly is a simple and robust method for producing structurally tailored thin film biomaterials, of thickness ca. 10nm, containing biofunctional ligands. We investigate the LbL formation of multilayer films composed of polymers of biological origin (poly(L-lysine) (PLL) and dextran sulfate (DS)), the adsorption of fibronectin (Fn)–a matrix protein known to […]
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6 years ago

Using Complementary Acoustic and Optical Techniques for Quantitative Monitoring of Biomolecular Adsorption at Interfaces

Abstract The great wealth of different surface sensitive techniques used in biosensing, most of which claim to measure adsorbed mass, can at first glance look unnecessary. However, with each technique relying on a different transducer principle there is something to be gained from a comparison. In this tutorial review, different optical and acoustic evanescent techniques […]
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6 years ago