QCM-I in Glove Box

Quartz Crystal Microbalance in Glove Box

MicroVacuum’s high performance QCM-I device is a Quartz Crystal Microbalance System with impedance analyses and dissipation monitoring (QCM -D), the Glove-Box QCM-I takes the high performance QCM-I instrument into a format suitable for mounting in a Glove-box or controlled atmosphere chamber and also includes the option of a wider temperature range e.g. between -30 °C and 80 °C.
The Principles of QCM-I (QCM-D) - Figure 1

The Principles of QCM-I

Quartz Crystal Microbalance with Impedance Analysis (QCM-I) and Dissipation Monitoring (QCM-D) The Quartz Crystal Microbalance is a well-established and sensitive technique used to measure the interactions of molecules, polymers and biological assemblies with a sensor surface, in air or liquid, label-free and in real time. It is based on the change in resonant frequency of […]
In situ viscoelastic properties and chain conformations of heavily hydrated carboxymethyl dextran layers

A comparative study using OWLS and QCM-I chips coated with waveguide material

We are very proud that both of our OWLS and QCM-I biosensor systems were used in the recent comparative study published on Nature.com See the abstract below and visit Nature.com to read the full publication. In situ viscoelastic properties and chain conformations of heavily hydrated carboxymethyl dextran layers: a comparative study using OWLS and QCM-I […]

Variations in Coupled Water, Viscoelastic Properties, and Film Thickness of a Mefp-1 Protein Film during Adsorption and Cross-Linking:  A Quartz Crystal Microbalance with Dissipation Monitoring, Ellipsometry, and Surface Plasmon Resonance Study

Abstract We have measured the time-resolved adsorption kinetics of the mussel adhesive protein (Mefp-1) on a nonpolar, methyl-terminated (thiolated) gold surface, using three independent techniques:  quartz crystal microbalance with dissipation monitoring (QCM-D), surface plasmon resonance, and ellipsometry. The QCM-D and ellipsometry data shows that, after adsorption to saturation of Mefp-1, cross-linking of the protein layer […]

Fibronectin terminated multilayer films: protein adsorption and cell attachment studies

Abstract Electrostatically driven layer-by-layer (LbL) assembly is a simple and robust method for producing structurally tailored thin film biomaterials, of thickness ca. 10nm, containing biofunctional ligands. We investigate the LbL formation of multilayer films composed of polymers of biological origin (poly(L-lysine) (PLL) and dextran sulfate (DS)), the adsorption of fibronectin (Fn)–a matrix protein known to […]