Scientific Publications

The Measurement of Protein and Nano-Particle Adsorption using QCM-I

QCM-I is a powerful technique for measuring the adsorption or binding of polymers, proteins, nano-particles and other molecules to a surface. Multi-parametric data is obtained in real time, detailing changes of the hydrated mass and rigidity of layers coupled to the sensor surface. Here, the mass and viscoelastic changes can be understood for a range […]
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3 years ago

Combining QCM-I and OWLS Measurements to Understand Polymer Multilayer Deposition Processes

Understanding the adsorption of surface active layers is complex. The most useful real-time techniques provide multiple pieces of information, however a much clearer picture can be obtained by combining such techniques.1 QCM-I measures changes relating to the hydrated mass and rigidity of surface layers. Combining this with an optical technique such as OWLS, the “dry mass” […]
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3 years ago

QCM-I Setup for Measuring the Effect of Humidity on Thin Films

The QCM-I and QCM-I Mini systems are designed to be modular so that they can be configured to use the sensors and sample environments that are most appropriate for the user’s experiments. This technical note summarizes the basic configurations that can be used with the QCM-I for measuring the effect of changes in humidity on […]
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3 years ago
Measuring Thick Coconut Oil Films and Cleaning using QCM-I - Figure 1

Measuring Thick Coconut Oil Films and Cleaning using QCM-I

Micron-thick films of Coconut Oil can be formed by spin-coating and the thickness of the solid films estimated using QCM-I. The viscoelastic changes in the layers can be observed during melting and subsequent structural reorganization on re-solidification. This data can be compared to the effect of dish-cleaning detergent on the films at low temperatures in […]
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3 years ago

Synchronizing QCM-I (QCM-D) Measurements Using the Digital IO Port

The BioSense 3 software controls and records experiments using the Quartz Crystal Microbalance with Impedance (QCM-I) instrument. Other instrumentation can also be controlled with the software to provide integrated experiments, e.g. Gamry potentiostats for electrochemical QCM-I measurements. Other equipment can also be synchronized with the QCM-I experiment using the digital In/Out port. This technical note […]
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3 years ago
Measurement of Polymer Multilayer Deposition using QCM-I QCM-D Figure 1

Measurement of Polymer Multilayer Deposition using QCM-I

The electrostatically driven adsorption of polymer and nano-particle multilayers is a well-established method for the physical and chemical transformation of surfaces to produce highly tailored and often “smart”, environmentally sensitive interfaces. The deposition process can be sensitively monitored using QCM-I, which provides information on the hydrated mass of the multilayer as well as its physical […]
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4 years ago
Handbook of Biosensors and Biochips (2 Volume set)

Handbook of Biosensors and Biochips (2 Volume set)

With contributions from experts in the field, the Handbook of Biosensors and Biochips provides an essential reference, underpinning many of the applications used in medical diagnostics, environmental control and pharmaceutical and food industries. It presents an invaluable addition for those in both academia and industry.
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4 years ago
Label-Free Biosensing- Advanced Materials, Devices and Applications (Springer Series on Chemical Sensors and Biosensors)

Label-Free Biosensing: Advanced Materials, Devices and Applications (Springer Series on Chemical Sensors and Biosensors)

This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of […]
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4 years ago
Handbook of Surface Plasmon Resonance

Handbook of Surface Plasmon Resonance

Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events and with the biosensor field expanding more applications are being found. In response to the market, an update to the original title which was published in 2008 is now appropriate. With over fifty percent of the material being updated, […]
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4 years ago